Article
DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis.
Journal of hepatology - 1 Dec 1994
Onishi S, Sakamaki T, Maeda T, Iwamura S, Tomita A, Saibara T, Yamamoto Y
Abstract excerpt
The association between human leukocyte antigens and primary biliary cirrhosis is controversial, but major histocompatibility complex class II antigen DR8 was recently reported to be associated with increased susceptibility for primary biliary cirrhosis in some Caucasians and Japanese. Accordingl...
Topics
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Sequence
- Asian People
- DNA
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Japan
- Liver Cirrhosis, Biliary
- Male
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction