Article
Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM.
Diabetes - 1 Jan 1994
van Endert P M, Liblau R S, Patel S D, Fugger L, Lopez T, Pociot F, Nerup J, McDevitt H O
Abstract excerpt
Susceptibility to insulin-dependent diabetes mellitus (IDDM) is greatly influenced by polymorphisms in the genes of the class II region of the human leukocyte antigen (HLA) complex. The complexity of this genetic association and the lack of a direct proof of involvement of HLA class II genes in h...
Topics
- ATP Binding Cassette Transporter, Subfamily B, Member 2
- ATP Binding Cassette Transporter, Subfamily B, Member 3
- ATP-Binding Cassette Transporters
- Adult
- Alleles
- Amino Acid Sequence
- Base Sequence
- Carrier Proteins
- Codon
- Cysteine Endopeptidases
- DNA Primers
- DNA Probes
- Diabetes Mellitus, Type 1
- Female
- Genes, MHC Class I
- Genes, MHC Class II
- Histocompatibility Antigens Class II
- Humans