Article
Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis.
Neurology - 1 Jun 1993
Liblau R, van Endert P M, Sandberg-Wollheim M, Patel S D, Lopez M T, Land S, Fugger L, McDevitt H O
Abstract excerpt
The association between multiple sclerosis (MS) and alleles of the HLA class II genes indicates that at least one MS susceptibility gene is linked to the HLA class II region. However, the actual locus responsible has not been precisely identified. The recent cloning of new genes involved in antigen processing that map within the HLA class II region led us to investigate--using the restriction fragment length...
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