Chemotactic and osmotic signals share a cGMP transduction pathway in Dictyostelium discoideum.

doi:10.1016/s0014-5793(98)00183-5

Back to search

Article

Chemotactic and osmotic signals share a cGMP transduction pathway in Dictyostelium discoideum.

FEBS letters - 13 Mar 1998

Kuwayama H, Van Haastert P J

Abstract excerpt

In the ameboid eukaryote Dictyostelium discoideum, chemotactic stimulation by cAMP induces an increase of intracellular cGMP and subsequently the phosphorylation of myosin heavy chain II. Resistance to high osmotic stress also requires transient increases of intracellular cGMP and phosphorylation...

Topics

Animals
Carrier Proteins
Chemotaxis
Cyclic GMP
Dictyostelium
GTP-Binding Proteins
Inositol 1,4,5-Trisphosphate
Intracellular Signaling Peptides and Proteins
Mutation
Osmosis
Receptors, Cyclic AMP
Signal Transduction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.