Article
Chemotactic and osmotic signals share a cGMP transduction pathway in Dictyostelium discoideum.
FEBS letters - 13 Mar 1998
Kuwayama H, Van Haastert P J
Abstract excerpt
In the ameboid eukaryote Dictyostelium discoideum, chemotactic stimulation by cAMP induces an increase of intracellular cGMP and subsequently the phosphorylation of myosin heavy chain II. Resistance to high osmotic stress also requires transient increases of intracellular cGMP and phosphorylation of myosin heavy chain II, although the kinetics is much slower than for chemotaxis. To examine if chemotaxis and...
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