Article
Methods for predicting carcinogenic hazards: new opportunities coming from recent developments in molecular oncology and SAR studies.
Mutation research - 13 Jun 1997
Taningher M, Malacarne D, Mancuso T, Peluso M, Pescarolo M P, Parodi S
Abstract excerpt
Without epidemiological evidence, and prior to either short-term tests of genotoxicity or long-term tests of carcinogenicity in rodents, an initial level of information about the carcinogenic hazard of a chemical that perhaps has been designed on paper, but never synthesized, can be provided by s...
Topics
- Animals
- Animals, Genetically Modified
- Carcinogenicity Tests
- Carcinogens
- DNA Adducts
- Electronic Data Processing
- Humans
- Mice
- Mutagens
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Structure-Activity Relationship