Article
DNA sequence requirements for Ah receptor/Arnt recognition determined by in vitro transcription.
Receptor - 1 Jan 1994
McLane K E, Whitlock J P
Abstract excerpt
The enhancer of the mouse cytochrome P450 cyp1a1 gene, which contains six binding sites (A-F) for the Ah receptor (AhR), has been a useful model system for studying the mechanism of AhR-mediated activation of transcription. In the presence of ligand, AhR interacts with its dimerization partner, Arnt, and the heteromeric complex is able to bind DNA. In the present study, we test the effects of single base pair...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
