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Article

Identification of the Ah-receptor structural determinants for ligand preferences.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Sept 2012

Xing Yongna, Nukaya Manabu, Satyshur Kenneth A, Jiang Li, Stanevich Vitali, Korkmaz Elif Nihal, Burdette Lisa, Kennedy Gregory D, Cui Qiang, Bradfield Christopher A

Abstract excerpt

The aryl hydrocarbon receptor (AHR) is a transcription factor that responds to diverse ligands and plays a critical role in toxicology, immune function, and cardiovascular physiology. The structural basis of the AHR for ligand promiscuity and preferences is critical for understanding AHR function...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22659362
DOI: 10.1093/toxsci/kfs194
PMCID: PMC3491955

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22659362-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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