Article
The aryl hydrocarbon receptor regulates mouse Fshr promoter activity through an e-box binding site.
Biology of reproduction - 1 Mar 2012
Teino Indrek, Kuuse Sulev, Ingerpuu Sulev, Maimets Toivo, Tiido Tarmo
Abstract excerpt
The aryl hydrocarbon receptor (AHR) mediates the toxicity of a variety of environmental chemicals. Apart from this, an understanding is emerging that the AHR has a fundamental role in female reproduction. Evidence suggests that AHR participates in regulation of follicle-stimulating hormone receptor (Fshr) transcript level in mouse ovary by binding to the promoter of this gene in vivo. The purpose of this study...
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