p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors.

doi:10.1002/mc.2940060210

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors.

Molecular carcinogenesis - 1 Jan 1992

Kress S, König J, Schweizer J, Löhrke H, Bauer-Hofmann R, Schwarz M

Abstract excerpt

Mutations in the p53 gene are frequent genetic alterations in human hepatocellular carcinomas. We have examined, by single-strand conformation polymorphism analysis of polymerase chain reaction products, a total of 93 carcinogen-induced liver tumors from mice of three different strains (C3H/He, C...

Topics

Animals
Base Sequence
DNA Fingerprinting
Electrophoresis, Polyacrylamide Gel
Genes, p53
Keratins
Liver Neoplasms, Experimental
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Molecular Sequence Data
Mutation
Nucleic Acid Hybridization
Oligonucleotides
Polymerase Chain Reaction
Polymorphism, Genetic

Source

Open in PubMed

Identifiers

PMID: 1382443
DOI: 10.1002/mc.2940060210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1382443-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics