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Article

p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors.

Molecular carcinogenesis - 1 Jan 1992

Kress S, König J, Schweizer J, Löhrke H, Bauer-Hofmann R, Schwarz M

Abstract excerpt

Mutations in the p53 gene are frequent genetic alterations in human hepatocellular carcinomas. We have examined, by single-strand conformation polymorphism analysis of polymerase chain reaction products, a total of 93 carcinogen-induced liver tumors from mice of three different strains (C3H/He, C57BL/6J, and B6C3F1) for the presence of p53 aberrations. Hepatoma lines, established from 12 liver tumors, were also...

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Identifiers

PMID: 1382443
DOI: 10.1002/mc.2940060210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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