Metabolic oxidation phenotypes as markers for susceptibility to lung cancer.

doi:10.1038/312169a0

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Article

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer.

Nature - 1 Jan 2000

Ayesh R, Idle J R, Ritchie J C, Crothers M J, Hetzel M R

Abstract excerpt

That bronchial carcinoma is not an inevitable consequence of cigarette smoking has stimulated the search for host factors that might influence the susceptibility of the individual smoker. One plausible host factor would be a polymorphic gene controlling the metabolic oxidative activation of chemi...

Topics

Carcinoma, Bronchogenic
Debrisoquin
Disease Susceptibility
Heterozygote
Homozygote
Humans
Lung Neoplasms
Phenotype
Smoking

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