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Article

Mutations in the mitochondrial split gene COXI are preferentially located in exons: a mapping study of 170 mutants.

Molecular & general genetics : MGG - 20 Feb 1995

Netter P, Robineau S, Lemaire C

Abstract excerpt

We have analysed the precise location of a large number (170) of mutations affecting the structural gene for subunit I of the cytochrome c oxidase complex. This gene, COXI, is 12.9 kb long and the major part of the sequence (i.e. 11.3 kb) is composed of introns. Several conclusions can be drawn from this study: (1) A significant proportion (84/170) of the mutations cannot be assigned to a single position within...

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Identifiers

PMID: 7891658
DOI: 10.1007/BF00290448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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