Article
Mutations in the mitochondrial split gene COXI are preferentially located in exons: a mapping study of 170 mutants.
Molecular & general genetics : MGG - 20 Feb 1995
Netter P, Robineau S, Lemaire C
Abstract excerpt
We have analysed the precise location of a large number (170) of mutations affecting the structural gene for subunit I of the cytochrome c oxidase complex. This gene, COXI, is 12.9 kb long and the major part of the sequence (i.e. 11.3 kb) is composed of introns. Several conclusions can be drawn f...
Topics
- Base Sequence
- Chromosome Mapping
- DNA, Fungal
- DNA, Mitochondrial
- Electron Transport Complex IV
- Exons
- Introns
- Molecular Sequence Data
- Mutation
- Saccharomyces cerevisiae
