Article
Molecular and biochemical analysis of Saccharomyces cerevisiae cox1 mutants.
Current genetics - 1 Aug 1998
Lemaire C, Robineau S, Netter P
Abstract excerpt
We report on the molecular and biochemical analysis of a set of 13 respiratory deficient mutants of Saccharomyces cerevisiae which are specifically altered in COX1, the gene encoding the subunit Cox1p of cytochrome c oxidase. DNA sequence analysis shows that three are due to frameshift mutations, two to nonsense mutations, and eight to missense mutations. All, except the missense mutant S157L, have impaired...
Topics
- Amino Acid Sequence
- Base Sequence
- Codon, Nonsense
- DNA, Fungal
- Electron Transport Complex IV
- Frameshift Mutation
- Genes, Fungal
- Immunoblotting
- Models, Molecular
- Molecular Sequence Data
- Mutation