Article
The mobile group I intron 3 alpha of the yeast mitochondrial COXI gene encodes a 35-kDa processed protein that is an endonuclease but not a maturase.
The Journal of biological chemistry - 30 Jun 1995
Guo W W, Moran J V, Hoffman P W, Henke R M, Butow R A, Perlman P S
Abstract excerpt
Three mitochondrial mutants were characterized that block the splicing of aI3 alpha, a mobile group I intron of the COXI gene of yeast mtDNA. Mutant C1085 alters helical structures known to be important for splicing of group I introns. M44 and C1072 are point mutants in exon 3 that block correct splicing but allow some splicing at cryptic 5'-splice sites. M44 alters the P1 helix needed for 5'-splice site...
Topics
- Base Sequence
- DNA, Fungal
- DNA, Mitochondrial
- Endonucleases
- Endoribonucleases
- Fungal Proteins
- Genes, Fungal
- Introns
- Molecular Sequence Data
- Mutation
- Nucleotidyltransferases