Article
Analysis of MTS1/CDK4 in female breast carcinomas.
Cancer letters - 2 Mar 1995
Rush E B, Abouezzi Z, Borgen P I, Anelli A
Abstract excerpt
Multiple factors, both environmental and genetic, are thought to play roles in breast carcinogenesis. The recently cloned multiple tumor suppressor gene (MTS1), the product of which interacts with CDK4 to regulate cell growth, has been found to be mutated with high frequency in a variety of cell lines as well as primary tumors of different histologic types. Using PCR-SSCP, we analyzed exons one (126 bp) and two...
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