Article
Analysis of MTS1/CDK4 in female breast carcinomas.
Cancer letters - 2 Mar 1995
Rush E B, Abouezzi Z, Borgen P I, Anelli A
Abstract excerpt
Multiple factors, both environmental and genetic, are thought to play roles in breast carcinogenesis. The recently cloned multiple tumor suppressor gene (MTS1), the product of which interacts with CDK4 to regulate cell growth, has been found to be mutated with high frequency in a variety of cell...
Topics
- Adenocarcinoma
- Adult
- Aged
- Breast
- Breast Neoplasms
- Cell Division
- Chromosomes, Human, Pair 9
- Codon
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinases
- Female
- Genes, Tumor Suppressor
- Humans
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Protein Serine-Threonine Kinases