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Article

Discrimination between thymic epithelial cells and peripheral antigen-presenting cells in the induction of immature T cell differentiation.

Immunity - 1 Aug 1994

Poirier G, Lo D, Reilly C R, Kaye J

Abstract excerpt

During their intrathymic migration, immature CD4+ CD8+ thymocytes that express a TCR able to recognize the expressed MHC molecules are positively selected, i.e., complete their differentiation program and become mature T cells. Using the immature CD4+CD8+ T cell line DPK, which can be induced to...

Topics

Animals
Antigen-Presenting Cells
CD4-Positive T-Lymphocytes
CD8-Positive T-Lymphocytes
Cell Differentiation
Cell Line
Cellular Senescence
Epithelial Cells
Mice
Mice, Inbred Strains
Mice, Transgenic
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Antigen, T-Cell

T-Lymphocytes

Thymus Gland

Source

Identifiers

PMID: 7882169
DOI: 10.1016/1074-7613(94)90069-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7882169-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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