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Article

Dynamics of positive and negative selection in the thymus: review and hypothesis.

Immunology letters - 1 Jun 1990

Marusić-Galesić S, Pavelić K

Abstract excerpt

T cells recognize with a single receptor both a product of antigens processed by antigen presenting cells (APC1) and a self-marker molecule, encoded by the major histocompatibility complex (MHC, a property termed MHC-restricted recognition of antigen). During their differentiation in the thymus, T cells "learn" what to regard as self-MHC molecules, and only the cells once able to recognize antigen in the context...

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Source

Identifiers

PMID: 2200750
DOI: 10.1016/0165-2478(90)90040-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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