Genetic heterogeneity in familial malignant melanoma.

doi:10.1093/hmg/3.12.2195

Back to search

Article

Genetic heterogeneity in familial malignant melanoma.

Human molecular genetics - 1 Dec 1994

MacGeoch C, Bishop J A, Bataille V, Bishop D T, Frischauf A M, Meloni R, Cuzick J, Pinney E, Spurr N K

Abstract excerpt

Following reports of linkage to chromosome 9p in families with malignant melanoma, we have been studying a series of UK families. Six families were selected with three or more cases of malignant melanoma. We have used a total of twelve markers mapping in the interval 9p13-p23 and constructed a se...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Base Sequence
Chromosomes, Human, Pair 9
DNA, Neoplasm
Exons
Female
Genes, Tumor Suppressor
Genetic Heterogeneity
Genetic Linkage
Genetic Markers
Haplotypes
Humans
Male
Melanoma
Middle Aged

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.