Article
Confirmation of chromosome 9p linkage in familial melanoma.
American journal of human genetics - 1 Oct 1993
Nancarrow D J, Mann G J, Holland E A, Walker G J, Beaton S C, Walters M K, Luxford C, Palmer J M, Donald J A, Weber J L
Abstract excerpt
Malignant melanoma occurs as a familial cancer in 5%-10% of cases where it segregates in a manner consistent with autosomal dominant inheritance. Evidence from cytogenetics, fine-mapping studies of deletions in melanomas, and recent linkage studies supports the location of a human melanoma predis...
Topics
- Adult
- Age of Onset
- Chromosomes, Human, Pair 9
- Genetic Linkage
- Genetic Predisposition to Disease
- Humans
- Lod Score
- Melanoma
- Middle Aged