Article
A kinase-cyclin pair in the RNA polymerase II holoenzyme.
Nature - 9 Mar 1995
Liao S M, Zhang J, Jeffery D A, Koleske A J, Thompson C M, Chao D M, Viljoen M, van Vuuren H J, Young R A
Abstract excerpt
The RNA polymerase II holoenzyme consists of RNA polymerase II, a subset of general transcription factors, and regulatory proteins known as SRB proteins. The genes encoding SRB proteins were isolated as suppressors of mutations in the RNA polymerase II carboxy-terminal domain (CTD). The CTD and SRB proteins have been implicated in the response to transcriptional regulators. We report here the isolation of two new...
Topics
- Amino Acid Sequence
- Cyclin-Dependent Kinase 8
- Cyclin-Dependent Kinases
- Cyclins
- Fungal Proteins
- Molecular Sequence Data
- Mutation
- Protein Serine-Threonine Kinases
- RNA Polymerase II
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins