Article
Functional analysis of the Ume3p/ Srb11p-RNA polymerase II holoenzyme interaction.
Gene expression - 1 Jan 1999
Cooper K F, Strich R
Abstract excerpt
The yeast C-type cyclin Ume3p/Srb11p and its cyclin-dependent kinase (Cdk) Ume5p are required for the full repression of genes involved in the stress response or meiosis. This cyclin-Cdk kinase copurifies with the RNA polymerase II holoenzyme complex, suggesting it functions through modification of the transcriptional machinery. This report describes two domains required for Ume3p-RNA Pol II holoenzyme...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
