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Article

A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast.

The Journal of biological chemistry - 15 Nov 2002

Borggrefe Tilman, Davis Ralph, Erdjument-Bromage Hediye, Tempst Paul, Kornberg Roger D

Abstract excerpt

The Srb8, -9, -10, and -11 proteins of yeast have been isolated as a discrete, stoichiometric complex. The isolated complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II at serines 2 and 5. In addition to the previously reported human homologs of Srb10 and 11, we have identified TRAP230/ARC240 and TRAP240/ARC250 as the human homologs of Srb8 and Srb9, showing the entire...

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PMID: 12200444
DOI: 10.1074/jbc.M207195200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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