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Article

Experimental lyme arthritis in the absence of interleukin-4 or gamma interferon.

Infection and immunity - 1 Jul 1999

Brown C R, Reiner S L

Abstract excerpt

Genetic resistance and susceptibility to experimental Lyme arthritis have been linked with the production of interleukin-4 (IL-4) or gamma interferon (IFN-gamma), respectively. To determine the absolute requirement for these cytokines in disease outcome, we compared arthritis development in wild-type, IL-4-deficient (IL-4 degrees ), and IFN-gamma-deficient (IFN-gamma degrees ) mice. While susceptible C3H mice...

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Identifiers

PMID: 10377109
DOI: 10.1128/IAI.67.7.3329-3333.1999
PMCID: PMC116514

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