Article
[Aberrations of tumor suppressor genes in hepatocellular carcinomas].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Sept 1994
Fujimoto Y
Abstract excerpt
Mutation of the p53 gene and loss of heterozygosity of the p53, Rb, APC, and MCC genes were examined in 14 hepatocellular carcinomas (HCCs) diagnosed at the third department of internal medicine in Asahikawa Medical College. Mutations in the p53 gene were detected in 4 HCCs out of 14 (25%) using...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Carcinoma, Hepatocellular
- Female
- Genes, Tumor Suppressor
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation