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[Aberrations of tumor suppressor genes in hepatocellular carcinomas].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 Sept 1994

Fujimoto Y

Abstract excerpt

Mutation of the p53 gene and loss of heterozygosity of the p53, Rb, APC, and MCC genes were examined in 14 hepatocellular carcinomas (HCCs) diagnosed at the third department of internal medicine in Asahikawa Medical College. Mutations in the p53 gene were detected in 4 HCCs out of 14 (25%) using polymerase chain reaction-single strand conformational polymorphism. The sites of the mutations showed a random...

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Identifiers

PMID: 7868063

Genes

APC
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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