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Article

Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development.

Cell - 24 Feb 1995

Li W, Ohlmeyer J T, Lane M E, Kalderon D

Abstract excerpt

Reduced protein kinase A (PKA) activity in anterior imaginal disc cells leads to cell-autonomous induction of decapentaplegic (dpp), wingless (wg), and patched (ptc) transcription that is independent of hedgehog (hh) gene activity. The resulting nonautonomous adult wing and leg pattern duplications are largely due to induced dpp and wg expression and resemble phenotypes elicited by ectopic hh expression....

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PMID: 7867063
DOI: 10.1016/0092-8674(95)90509-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Function of protein kinase A in hedgehog signal transduction and Drosophila imaginal disc development.PMID 7867063Read ↗

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