Article
Positional signaling by hedgehog in Drosophila imaginal disc development.
Development (Cambridge, England) - 1 Jan 1995
Felsenfeld A L, Kennison J A
Abstract excerpt
We describe a dominant gain-of-function allele of the segment polarity gene hedgehog. This mutation causes ectopic expression of hedgehog mRNA in the anterior compartment of wing discs, leading to overgrowth of tissue in the anterior of the wing and partial duplication of distal wing structures. The posterior compartment of the wing is unaffected. Other imaginal derivatives are affected, resulting in duplications...
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