Article
cAMP-dependent protein kinase and hedgehog act antagonistically in regulating decapentaplegic transcription in Drosophila imaginal discs.
Cell - 24 Feb 1995
Pan D, Rubin G M
Abstract excerpt
Localized expression of decapentaplegic (dpp) is required for proper development of the Drosophila imaginal discs. Using genetic mosaics, we show that in the anterior compartment of appendage discs and anterior to the morphogenetic furrow in the eye disc, cells that lack cAMP-dependent protein ki...
Topics
- Animals
- Cyclic AMP-Dependent Protein Kinases
- Drosophila
- Drosophila Proteins
- Eye
- Fluorescent Antibody Technique
- Gene Expression Regulation
- Genes, Reporter
- Hedgehog Proteins
- Insect Hormones
- Models, Genetic
- Mutation
- Proteins
- Signal Transduction
- Suppression, Genetic
- Transcription, Genetic
- Wings, Animal