Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Nov 1994

Berkower C, Loayza D, Michaelis S

Abstract excerpt

STE6, a member of the ATP binding cassette (ABC) transporter superfamily, is a membrane protein required for the export of the a-factor mating pheromone in Saccharomyces cerevisiae. To initiate a study of the intracellular trafficking of STE6, we have examined its half-life and localization. We report here that STE6 is metabolically unstable in a wild-type strain, and that this instability is blocked in a pep4...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Membrane
Share to Fungal Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutation

Share to Saccharomyces cerevisiae

Share to Saccharomyces cerevisiae Proteins

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 7865884
DOI: 10.1091/mbc.5.11.1185
PMCID: PMC301145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae.PMID 7865884Read ↗

The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.Semantic proximity Read ↗

Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Elimination of defective alpha-factor pheromone receptors.Semantic proximity Read ↗

The internalization of yeast Ste6p follows an ordered series of events involving phosphorylation, ubiquitination, recognition and endocytosis.Semantic proximity Read ↗

A striking quality control subcompartment in Saccharomyces cerevisiae: the endoplasmic reticulum-associated compartment.Semantic proximity Read ↗

A family of small coiled-coil-forming proteins functioning at the late endosome in yeast.Semantic proximity Read ↗

Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.Semantic proximity Read ↗

Mutations affecting phosphorylation, ubiquitination and turnover of the ABC-transporter Ste6.Semantic proximity Read ↗

Nuclear export and plasma membrane recruitment of the Ste5 scaffold are coordinated with oligomerization and association with signal transduction components.Semantic proximity Read ↗

An endosome-to-plasma membrane pathway involved in trafficking of a mutant plasma membrane ATPase in yeast.Semantic proximity Read ↗

The ankyrin repeat-containing protein Akr1p is required for the endocytosis of yeast pheromone receptors.Semantic proximity Read ↗

Conditional inactivation of Aspergillus nidulans sarA(SAR1) uncovers the morphogenetic potential of regulating endoplasmic reticulum (ER) exit.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.