Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.

The EMBO journal - 1 Dec 1991

Berkower C, Michaelis S

Abstract excerpt

STE6, the yeast a-factor transporter, is a member of the ATP binding cassette protein superfamily, which also includes the mammalian multidrug resistance protein and the cystic fibrosis gene product. These proteins contain two homologous halves, each with six membrane spanning segments and a pred...

Topics

ATP-Binding Cassette Transporters
Adenosine Triphosphate
Amino Acid Sequence
Biological Transport
Carrier Proteins
Fungal Proteins
Molecular Sequence Data
Multigene Family
Mutagenesis, Site-Directed
Mutation
Plasmids
Precipitin Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sequence Alignment

Structure-Activity Relationship

Source

Open in PubMed Open full text

Identifiers

PMID: 1935899
DOI: 10.1002/j.1460-2075.1991.tb04947.x
PMCID: PMC453114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1935899-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette (ABC) protein superfamily.PMID 1935899Read ↗

Functional and physical interactions between partial molecules of STE6, a yeast ATP-binding cassette protein.Semantic proximity Read ↗

Effects of nucleotide binding fold mutations on STE6, a yeast ABC protein.Semantic proximity Read ↗

Mutations affecting phosphorylation, ubiquitination and turnover of the ABC-transporter Ste6.Semantic proximity Read ↗

The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export.Semantic proximity Read ↗

Mutations within the first LSGGQ motif of Ste6p cause defects in a-factor transport and mating in Saccharomyces cerevisiae.Semantic proximity Read ↗

Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae.Semantic proximity Read ↗

Functional complementation of yeast ste6 by a mammalian multidrug resistance mdr gene.Semantic proximity Read ↗

The internalization of yeast Ste6p follows an ordered series of events involving phosphorylation, ubiquitination, recognition and endocytosis.Semantic proximity Read ↗

Ste6p mutants defective in exit from the endoplasmic reticulum (ER) reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae.Semantic proximity Read ↗

Expression of MFA1 and STE6 is sufficient for mating type-independent secretion of yeast a-factor, but not mating competence.Semantic proximity Read ↗

Role of the ABC transporter Ste6 in cell fusion during yeast conjugation.Semantic proximity Read ↗

Isolation and characterization of SYS genes from yeast, multicopy suppressors of the functional loss of the transport GTPase Ypt6p.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.