Article
The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1.
Cell - 13 Nov 1992
Handeli S, Weintraub H
Abstract excerpt
The ts41 mutation of Chinese hamster cells was first isolated and characterized by Hirschberg and Marcus (1982) who showed that at nonpermissive temperature, cells accumulate up to 16C equivalents of DNA. Here we show that the mutation is recessive and at nonpermissive temperature, cells replicat...
Topics
- Animals
- Cell Cycle
- Cell Line
- Cloning, Molecular
- Cricetinae
- DNA Replication
- Flow Cytometry
- Genes, Recessive
- Genetic Complementation Test
- Mutation
- Nocodazole
- S Phase
- Temperature