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Article

The ts41 mutation in Chinese hamster cells leads to successive S phases in the absence of intervening G2, M, and G1.

Cell - 13 Nov 1992

Handeli S, Weintraub H

Abstract excerpt

The ts41 mutation of Chinese hamster cells was first isolated and characterized by Hirschberg and Marcus (1982) who showed that at nonpermissive temperature, cells accumulate up to 16C equivalents of DNA. Here we show that the mutation is recessive and at nonpermissive temperature, cells replicate their genome normally, but instead of going on into G2, M, and G1, they pass directly into a second S phase. Entry...

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Source

Identifiers

PMID: 1423617
DOI: 10.1016/0092-8674(92)90594-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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