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Article

Transforming growth factor-alpha and beta-amyloid precursor protein share a secretory mechanism.

The Journal of cell biology - 1 Feb 1995

Arribas J, Massagué J

Abstract excerpt

Cleavage and release of membrane protein ectodomains, a regulated process that affects many cell surface proteins, remains largely uncharacterized. To investigate whether cell surface proteins are cleaved through a shared mechanism or through multiple independent mechanisms, we mutagenized Chines...

Topics

Amyloid beta-Protein Precursor
Animals
Base Sequence
Biological Transport
CHO Cells
Cricetinae
Hydrolysis
Membrane Proteins
Molecular Sequence Data
Mutation
Oligodeoxyribonucleotides
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tetradecanoylphorbol Acetate

Transforming Growth Factor alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 7844156
DOI: 10.1083/jcb.128.3.433
PMCID: PMC2120346

Genes

APP
TFG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7844156-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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