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Article

Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells.

Immunopharmacology - 1 Jun 1997

Ehlers M R, Schwager S L, Chubb A J, Scholle R R, Brandt W F, Riordan J F

Abstract excerpt

Diverse membrane proteins are solubilized by a specific proteolytic cleavage in the stalk sequence adjacent to the membrane anchor, with release of the extracellular domain. Examples are the amyloid precursor protein, membrane-bound growth factors and angiotensin-converting enzyme (ACE). The identities and characteristics of the responsible proteases remain elusive. We have studied this process in Chinese hamster...

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Source

Identifiers

PMID: 9228557
DOI: 10.1016/s0162-3109(97)00032-5

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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