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Article

The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families.

Journal of autoimmunity - 1 Oct 1994

Pugliese A, Awdeh Z L, Alper C A, Jackson R A, Eisenbarth G S

Abstract excerpt

Several polymorphisms of the insulin gene and its flanking regions (INS region) are in linkage disequilibrium and confer susceptibility to insulin-dependent diabetes (IDDM). We have analysed INS AA and AB-BB genotypes at the 1,428 FokI site (3' of the insulin gene) in 217 patients with IDDM, 402 non-diabetic first degree relatives negative for insulin (IAA) and islet cell autoantibodies (ICA), and 116...

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Source

Identifiers

PMID: 7840860
DOI: 10.1006/jaut.1994.1053

Genes

INS

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Source receipt: pubmed, retrieved 7 Sept 2026.

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The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families.PMID 7840860Read ↗

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