Article
HLA-DQB1 genotypes and islet cell antibodies in the identification of siblings at risk for insulin-dependent diabetes (IDDM) in Finland. Childhood Diabetes in Finland (DiMe) Study Group.
Journal of autoimmunity - 1 Oct 1994
Reijonen H, Vähäsalo P, Karjalainen J, Ilonen J, Akerblom H K, Knip M
Abstract excerpt
The risk of progression to IDDM can be evaluated by diabetes-related autoantibodies such as cytoplasmic islet cell antibodies (ICA) or genetic determinants as markers. In this prospective study we wanted to estimate the predictive value of the combination of these markers in siblings of diabetic...
Topics
- Adolescent
- Adult
- Alleles
- Autoantibodies
- Autoimmune Diseases
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Finland
- Genetic Predisposition to Disease
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains