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Article

Additive susceptibility to insulin-dependent diabetes conferred by HLA-DQB1 and insulin genes.

Autoimmunity - 1 Jan 1994

She J X, Bui M M, Tian X H, Muir A, Wakeland E K, Zorovich B, Zhang L P, Liu M C, Thomson G, Maclaren N K

Abstract excerpt

Several genomic polymorphisms at the insulin (INS) gene and its flanking regions were analyzed in 197 unrelated Caucasian patients affected by insulin-dependent diabetes (IDDM) and 159 ethnically matched, normal controls ascertained from the South-Eastern United States. We found that the frequency of homozygotes for the common variant at the insulin gene was significantly increased in the diabetic population (RR...

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Identifiers

PMID: 7858104
DOI: 10.3109/08916939409007996

Genes

INS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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