Article
Influence of age on the associations among insulin autoantibodies, islet cell antibodies, and HLA DAQ1*0301-DQB1*0302 in siblings of patients with type 1 (insulin-dependent) diabetes mellitus. Belgian Diabetes Registry.
The Journal of clinical endocrinology and metabolism - 1 May 1994
Gorus F K, Vandewalle C L, Dorchy H, Van Crombrugge P, Schuit F C, Pipeleers D G
Abstract excerpt
In recent-onset type 1 (insulin-dependent) diabetes mellitus (IDDM), insulin autoantibodies (IAA) and islet cell antibodies (ICA) occur preferentially in young (< 10 yr) patients with the HLA DQA1*0301-DQB1*0302 risk haplotype. We investigated whether this association also exists in siblings of I...
Topics
- Adolescent
- Adult
- Age Factors
- Autoantibodies
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Female
- Follow-Up Studies
- Genotype
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Haplotypes
- Humans