Article
In vitro translation and membrane topology of rat recombinant mGluR1 alpha.
Neuropharmacology - 1 Sept 1994
Seal A J, Collingridge G L, Henley J M
Abstract excerpt
The structure and post-translational processing of the metabotropic glutamate receptor 1 alpha (mGluR1 alpha) was analysed by in vitro cell-free translation, protease protection and deglycosylation. We show that mGluR1 alpha can be synthesized in the rabbit-reticulocyte translation system to yield a predominant polypeptide product with an apparent molecular weight of 142 kDa. In the presence of dog-pancreatic...
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