Article
Expression of the candidate A-T gene ATDC is not detectable in a human cell line with a normal response to ionizing radiation.
International journal of radiation biology - 1 Dec 1994
Murnane J P, Zhu Y, Young B R, Christman M F
Abstract excerpt
Nucleotide sequence analysis of a candidate gene for A-T group D (ATDC) demonstrated that it is related to a group of proteins that contain both zinc finger and leucine zipper motifs. The presence of a leucine zipper suggested that this protein might form homodimers, and this was confirmed by mea...
Topics
- Amino Acid Sequence
- Ataxia Telangiectasia
- Base Sequence
- Cell Cycle
- Cell Line, Transformed
- Cloning, Molecular
- Colorectal Neoplasms
- DNA Probes
- DNA-Binding Proteins
- Fibroblasts
- Gene Expression
- Humans
- Leucine Zippers
- Molecular Sequence Data
- Phenotype
- RNA, Messenger
- Radiation Tolerance
- Transcription Factors