Ataxia-telangiectasia and cellular responses to DNA damage.

Article

Ataxia-telangiectasia and cellular responses to DNA damage.

Cancer research - 15 Dec 1995

Meyn M S

Abstract excerpt

Ataxia-telangiectasia (A-T) is a human disease characterized by high cancer risk, immune defects, radiation sensitivity, and genetic instability. Although A-T homozygotes are rare, the A-T gene may play a role in sporadic breast cancer and other common cancers. Abnormalities of DNA repair, geneti...

Topics

Apoptosis
Ataxia Telangiectasia
Cell Cycle
Chromosome Aberrations
DNA Damage
DNA Repair
Humans
Models, Theoretical
Mutation
Phenotype

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