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Article

Characterization of an acid-resistant mutant of foot-and-mouth disease virus.

Virology - 10 Jan 1995

Twomey T, France L L, Hassard S, Burrage T G, Newman J F, Brown F

Abstract excerpt

A foot-and-mouth disease virus mutant which is stable at pH 6.4 has been isolated from a virus of serotype A. In contrast to the parent (P) virus, which gave a mixture of large and small plaques in BHK21 cells and in a bovine kidney cell line, the acid-resistant (AR) virus gave small plaques which did not increase markedly in size after 24 hr. The infectivity titer of the acid-resistant virus was about 100-fold...

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PMID: 7831827
DOI: 10.1016/s0042-6822(95)80020-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Characterization of an acid-resistant mutant of foot-and-mouth disease virus.PMID 7831827Read ↗

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Adaptive value of foot-and-mouth disease virus capsid substitutions with opposite effects on particle acid stability.Semantic proximity Read ↗

Establishment of persistent infection with foot-and-mouth disease virus in BHK-21 cellsSemantic proximity Read ↗

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