Strain variation in the katG region of Mycobacterium tuberculosis.

doi:10.1111/j.1365-2958.1994.tb01291.x

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Article

Strain variation in the katG region of Mycobacterium tuberculosis.

Molecular microbiology - 1 Oct 1994

Zhang Y, Young D

Abstract excerpt

Southern blot analysis of chromosomal DNA from clinical isolates of Mycobacterium tuberculosis using cosmid DNA probes revealed extensive strain variation in the katG region of the genome. In addition to deletion of the katG gene itself in some isoniazid-resistant strains, adjacent DNA fragments...

Topics

Amino Acid Sequence
Bacterial Proteins
Base Sequence
Cosmids
Deoxyribonucleases, Type II Site-Specific
Drug Resistance, Microbial
Gene Deletion
Genes, Bacterial
Genetic Variation
Isoniazid
Molecular Sequence Data
Mycobacterium tuberculosis
Peroxidases
Polymerase Chain Reaction
Polymorphism, Genetic
Sequence Analysis, DNA
Species Specificity

Source

Open in PubMed

Identifiers

PMID: 7830574
DOI: 10.1111/j.1365-2958.1994.tb01291.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7830574-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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