PCR amplification of variable sequence upstream of katG gene to subdivide strains of Mycobacterium tuberculosis complex.

doi:10.1128/jcm.32.12.3070-3071.1994

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Article

PCR amplification of variable sequence upstream of katG gene to subdivide strains of Mycobacterium tuberculosis complex.

Journal of clinical microbiology - 1 Dec 1994

Goyal M, Young D, Zhang Y, Jenkins P A, Shaw R J

Abstract excerpt

PCR amplification of a species-specific 2-kb KpnI fragment of variable size located 10 kb upstream of the katG gene was used to subdivide 130 clinical isolates of Mycobacterium tuberculosis. Seven subtypes were identified, and their frequencies were distributed normally with respect to the size o...

Topics

Bacterial Typing Techniques
DNA, Bacterial
Genes, Bacterial
Genetic Variation
Humans
Mycobacterium tuberculosis
Polymerase Chain Reaction

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