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Article

Suppressor U1 snRNAs in Drosophila.

Genetics - 1 Oct 1994

Lo P C, Roy D, Mount S M

Abstract excerpt

Although the role of U1 small nuclear RNAs (snRNAs) in 5' splice site recognition is well established, suppressor U1 snRNAs active in intact multicellular animals have been lacking. Here we describe suppression of a 5' splice site mutation in the Drosophila melanogaster white gene (wDR18) by compensatory changes in U1 snRNA. Mutation of positions -1 and +6 of the 5' splice site of the second intron (ACG[GTGAGT to...

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Identifiers

PMID: 7828820
DOI: 10.1093/genetics/138.2.365
PMCID: PMC1206155

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