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Article

Origin and significance of the human DNase repertoire

2022-03-10

Abstract excerpt

The human genome contains four DNase1 and two DNase2 genes. The origin and functional specialization of this repertoire are not fully understood. Here we use genomics and transcriptomics data to infer the evolutionary history of DNases and investigate their biological significance. Both DNase1 and DNase2 families have expanded in vertebrates since ~650 million years ago before the divergence of jawless and jawed v...

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Literature Corpus work
cabe4ac3-ad09-5383-a004-b79ed89173da
DOI
10.21203/rs.3.rs-1419959/v1
Open publication

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Origin and significance of the human DNase repertoireDOI 10.21203/rs.3.rs-1419959/v1
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