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Article

Comparative biochemical properties of vertebrate deoxyribonuclease I.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Jan 2000

Fujihara Junko, Yasuda Toshihiro, Ueki Misuzu, Iida Reiko, Takeshita Haruo

Abstract excerpt

Deoxyribonuclease I (DNase I, EC 3.1.21.1) is an endonuclease that preferentially attacks double-stranded DNA in a Ca(2+)-dependent manner to produce oligonucleotides with 5'-phospho and 3'-hydroxy termini. This review deals with the biochemical properties and molecular evolution of DNase I. A comparative study of vertebrate DNase I from Chondrichthyes to Homo sapiens has been carried out. The optimal pH, the...

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Identifiers

PMID: 22885404
DOI: 10.1016/j.cbpb.2012.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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