Article

Evolutionary Tinkering Enriches the Hierarchical and Nested Structures in Amino Acid Sequences

2024-01-29

Abstract excerpt

<title>Abstract</title> <p>Genetic information often exhibits hierarchical and nested relationships, achieved through the reuse of repetitive subsequences such as duplicons and transposable elements, a concept termed ``evolutionary tinkering'' by Fran\c{c}ois Jacob. Current bioinformatics tools often struggle to capture these, particularly the nested, relationships. To address this, we utilized Ladderpath, a new...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fef24f0a-4835-5b44-97a8-5142fbc67a27
DOI: 10.21203/rs.3.rs-3440555/v2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evolutionary Tinkering Enriches the Hierarchical and Nested Structures in Amino Acid SequencesDOI 10.21203/rs.3.rs-3440555/v2Read

Building alternative splicing and evolution-aware sequence-structure maps for protein repeatsSemantic proximity Read

Genome-wide Pervasiveness and Localized Variation of <i>k</i> -mer-based Genomic Signatures in EukaryotesSemantic proximity Read

Simple and thorough detection of related sequences with position-varying probabilities of substitutions, insertions, and deletionsSemantic proximity Read

Conservation motifs - a novel evolutionary-based classification of proteinsSemantic proximity Read

A new index to find regions showing an unexpected variability or conservation in sequence alignments.Semantic proximity Read

Evolutionary trace report_maker: a new type of service for comparative analysis of proteins.Semantic proximity Read

Creative destruction: New protein folds from old.Semantic proximity Read

Improved DNA-versus-Protein Homology Search for Protein FossilsSemantic proximity Read

Symbolic Genome Structures: A Recursive Information Framework for Molecular Pattern EncodingSemantic proximity Read

Fractal Genomics of <i>SOD1</i> EvolutionSemantic proximity Read

Neweyes: a system for comparing biological sequences using the running Karp-Rabin Greedy String-Tiling algorithm.Semantic proximity Read

Rose: generating sequence families.Semantic proximity Read