Article
Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage patterns.
BMC bioinformatics - 7 Jul 2004
Reva Oleg N, Tümmler Burkhard
Abstract excerpt
BACKGROUND: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In this paper we analyzed oligonucleotide usage (OU) biases in a comprehensive collection of 155 completely sequenced bacterial chromosomes, 316 plasmids and 104 phages. RESULTS: Two global features were analyzed: pattern skew (PS) and...
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