Article
Response of the phosphoenolpyruvate carboxykinase gene to glucocorticoids depends on the integrity of the cAMP pathway.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Sept 1994
Angrand P O, Coffinier C, Weiss M C
Abstract excerpt
The phosphoenolpyruvate carboxykinase (PEPCK) gene is regulated at the transcriptional level by a variety of effectors in a tissue-specific fashion. In order to study the parameters involved in the tissue-specific hormonal regulation of the PEPCK gene, we have used a transient expression test in...
Topics
- Animals
- Base Sequence
- Cell Differentiation
- Cyclic AMP
- Dexamethasone
- Enzyme Induction
- Gene Expression Regulation, Enzymologic
- Genetic Variation
- Gluconeogenesis
- Liver Neoplasms, Experimental
- Molecular Sequence Data
- Phosphoenolpyruvate Carboxykinase (GTP)
- Promoter Regions, Genetic
- Rats
- Signal Transduction
- Transcription Factors
- Tumor Cells, Cultured