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Article

Characterization of a complex glucocorticoid response unit in the phosphoenolpyruvate carboxykinase gene.

Molecular and cellular biology - 1 Sept 1990

Imai E, Stromstedt P E, Quinn P G, Carlstedt-Duke J, Gustafsson J A, Granner D K

Abstract excerpt

The minimal DNA sequence required for glucocorticoid induction of the phosphoenolpyruvate carboxykinase (PEPCK) gene in H4IIE rat hepatoma cells was defined. This novel glucocorticoid response unit (GRU) spans about 110 base pairs (bp) and includes two receptor-binding elements plus two accessory factor-binding elements. Purified glucocorticoid receptor bound to two regions (GR1 and GR2) between -395 and -349 bp...

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Identifiers

PMID: 2388623
DOI: 10.1128/mcb.10.9.4712-4719.1990
PMCID: PMC361067

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CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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