Article
The role of the TATA box in the hormonal regulation of phosphoenolpyruvate carboxykinase gene expression.
Biochemical and biophysical research communications - 24 Oct 1995
Tebbey P W, Hall R K, Granner D K
Abstract excerpt
In this study, we analyzed the role of the TATA box in the regulation of the phosphoenolpyruvate carboxykinase (PEPCK) gene expression by dexamethasone (DEX), retinoic acid (RA), glucagon (via cAMP) and insulin (INS). The PEPCK TATA box (TATTTAAA) was absolutely required for both basal promoter a...
Topics
- Animals
- Base Sequence
- Cell Line
- Chloramphenicol O-Acetyltransferase
- Consensus Sequence
- Cyclic AMP
- DNA Primers
- Dexamethasone
- Gene Expression Regulation, Enzymologic
- Genetic Variation
- Insulin
- Kinetics
- Liver Neoplasms, Experimental
- Molecular Sequence Data
- Phosphoenolpyruvate Carboxykinase (GTP)
- Plasmids
- Rats
- Recombinant Proteins