Article
Glucocorticoid-stimulated CCAAT/enhancer-binding protein alpha expression is required for steroid-induced G1 cell cycle arrest of minimal-deviation rat hepatoma cells.
Molecular and cellular biology - 1 Oct 1996
Ramos R A, Nishio Y, Maiyar A C, Simon K E, Ridder C C, Ge Y, Firestone G L
Abstract excerpt
By genetic correlation with the growth-suppressible phenotype and direct functional tests, we demonstrate that the glucocorticoid-stimulated expression of the CCAAT/enhancer-binding protein alpha (C/EBP alpha) transcription factor is required for the steroid-mediated G1 cell cycle arrest of minim...
Topics
- Animals
- CCAAT-Enhancer-Binding Proteins
- Cell Cycle
- Cell Division
- Cell Line
- DNA Probes
- DNA Replication
- DNA-Binding Proteins
- Dexamethasone
- G1 Phase
- Glucocorticoids
- Humans
- Kinetics
- Liver Neoplasms, Experimental